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Bacitracin and Polymyxin B


Related terms
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    Related terms
    • Brand Names: U.S.: AK-Poly-BacT;PolycinT;Polysporin® [OTC]
    • Brand Names: Canada: LID-Pack®;Optimyxin®

    • It is used to avoid or treat skin infections.
    • It is used to stop or treat eye infections.
    • Bacitracin and polymyxin B works to harm the bacteria and fight the infection.


    How to take

    • Wash your hands before and after use.
    • Skin: Powder and ointment (topical):
    • Clean affected part before use. Make sure to dry well.
    • Skin: Powder (topical):
    • Sprinkle powder over affected skin.
    • Skin: Ointment (topical):
    • Put a thin layer on the affected skin and rub in gently.
    • The treated part may be covered with a dressing.
    • Eye:
    • For the eye only.
    • Tilt your head back.
    • Pull down lower eyelid of affected eye/eyes.
    • Put a thin film of ointment into the lower eye.
    • Close eye and roll eyeball around for 1 to 2 minutes.
    • Use other eye drugs 10 minutes after the ointment.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.


    • Store at room temperature.
    • Protect from heat.



    • If you have an allergy to bacitracin, polymyxin B, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Do not use longer than needed. A second infection may happen.
    • Use care when putting on. Staining may happen.
    • Avoid wearing contacts unless told to wear them by your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Swelling.
    • Itching.
    • Skin irritation.
    • Eye:
    • Blurred eyesight. Use care when driving or doing other tasks that call for clear eyesight.
    • Tearing.


    • Change in the health problem being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very bad skin irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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