Table of Contents > Drug > Clonidine Print



Related terms
Author information


    Related terms
    • Brand Names: U.S.: Catapres-TTS®-1;Catapres-TTS®-2;Catapres-TTS®-3;Catapres®;Duraclon®;Kapvay®
    • Brand Names: Canada: Apo-Clonidine®;Catapres®;Dixarit®;Dom-Clonidine;Novo-Clonidine;Nu-Clonidine

    • It is used to stop migraine headaches.
    • It is used to control pain when infused into the spine.
    • It is used to ease painful period (menstrual) cycles.
    • It is used to treat drug addiction and withdrawal.
    • It is used to treat flushing.
    • It is used to treat high blood pressure.
    • It is used to treat hot flashes caused by other drugs.
    • Rarely, it is used to treat loose stools having to do with high blood sugar (diabetes).
    • Clonidine lowers the body's release of adrenaline and other hormones that raise blood pressure, heart rate, and anxiety.
    • It works in the brain to ease pain.
    • It has a calming effect in children with attention deficit problems.


    How to take

    • All products:
    • Take as you have been told, even if you are feeling better.
    • Follow the diet and workout plan that your doctor told you about.
    • Tablet:
    • Take with or without food. Take with food if it causes an upset stomach.
    • Take last dose of the day at bedtime.
    • Extended release tablets:
    • Swallow whole. Do not chew or crush.
    • NexiclonT XR:
    • You may break the tablet in half. Do not chew or crush.
    • Oral suspension:
    • Shake well before use.
    • Skin patch:
    • Take off old patch first.
    • Put patch on clean, dry, healthy skin on the chest, back, or belly. Move the site with each new patch.
    • If the patch loosens, put tape over it to hold it in place.
    • Shot:
    • It is given into the spine.

    Missed Dose

    • Oral:
    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.
    • Skin patch:
    • Put on a missed patch as soon as you think about it after taking off the old one.
    • If it is close to the time for your next patch, place the new patch on.
    • Start a new timetable after the patch is put back on.
    • Do not put on 2 doses or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store patch and tablets at room temperature.
    • Protect tablets from light.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • The shot will be given to you in a hospital or doctor's office. You will not store it at home.



    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to clonidine or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


    • Do not run out of this drug.
    • Wear disease medical alert ID (identification).
    • You may have some heart tests before starting this drug. Talk with your doctor.
    • The patch may have metal. Take off the patch before an MRI.
    • If you have kidney disease, talk with your doctor.
    • Have your blood pressure and heart rate checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • If you are taking this drug and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
    • Dry eyes. Using artificial tears may help.
    • Skin irritation.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • Very hard stools (constipation).
    • Feeling very tired or weak.
    • Very bad skin irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

    Search Site